With Derma Fillers, you can have a natural beauty lift using the body’s own material.? Derma Fillers is a crystal-clear, non-animal, biodegradable gel based on the body’s naturally occurring substance, called hyaluronic acid. The gel is injected into the skin in tiny amounts with a very fine needle. The result is instantaneous and produces a long-lasting, natural enhancement that is gentle and safe to your skin. Treatment lasts six to twelve months.