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Crete Fertility Center

Crete Fertility Center

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Sofokli Venizelou & Arch. Makariou 56, Heraklion, 71202Greece

Very Good
from 107 users
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Opening hours

Monday08:30 - 16:30 | 17:30 - 20:30
Tuesday08:30 - 16:30 | 17:30 - 20:30
Wednesday08:30 - 16:30 | 17:30 - 20:30
Thursday09:00 - 16:30 | 17:30 - 20:30
Friday08:30 - 16:30 | 17:30 - 20:30
Enquire for a fast quote ★ Very Good ServiceScore™ 7.4 from 107 votes ★ 1 verified patient review. Visit our Fertility Clinic - Sofokli Venizelou & Arch. Makariou 56, Heraklion, 71202, Greece.

Popular Treatments

Fertility Specialist Consultation

Egg Donation

Egg Donation
Egg Donor
IVF - In Vitro Fertilisation
PGD - Preimplantation Genetic Diagnosis
Embryo Donation
Egg Freezing
ICSI - Intracytoplasmic Sperm Injection
IUI - Intrauterine Insemination
Embryo Freezing
See all treatments & prices

About Crete Fertility Center

Crete Fertility Centre, established more than 26 years ago by Dr Mattheos Fraidakis, has a long history in provision of quality services in assisted reproduction and reproductive surgery to the highest clinical and scientific standards without losing focus on the specific needs of couples who have sought care at Crete Fertility Centre.

Before founding Crete Fertility Centre, Dr Fraidakis was appointed for 3 years as clinical fellow and assistant researcher in the Academic Unit of Obstetrics, – Gynecology and & Reproduction Physiology, directed by Professor J.G.Grudzinskas, at the Royal London Hospital.

During this time Dr Fraidakis was also invited to join the medical team at Bridge Fertility Centre, one of the largest centers of Assisted Reproductive Technology(ART) in UK, at London Bridge Hospital. He also acted as visiting lecturer to the Academic Unit at the Royal London Hospital in ART and endoscopic surgery.

The international level, state of the art facilities, ensure that the highest quality of care is available. Medical and laboratory equipment are the most modern currently available, while standards of hygiene, health and safety are exemplary, in full compliance with the highest and strictest levels in Europe, that has already be confirmed by ISO Certification 9001:2008. Moreover, since November 8th 2017, it is one of the few clinics in Europe that has the DIN EN 15224 certification, which is the European framework for standards for the development and implementation of healthcare management systems.

It is noteworthy that Crete Fertility Centre is located on the seafront in one of the biggest and most beautiful islands in the Mediterranean, Crete. Thus, it is not surprising that couples travelling to this familiar holiday destination find that the tranquil setting on this beautiful island, lessens the inevitable anxiety and tension of imminent fertility treatment.

Add to this, our cost effective pricing policy (compared to other European and worldwide countries) and the highest standards medical expertise, science and health, establishes Crete Fertility Centre as the best choice for cost, effectiveness and safety for all ART needs.

Sono venuti da Australia a Centro Fertilita di Creta!
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Patient reviews

5.0 from 1 verified review
Elger, South Africa
( Verified user)

I was very happy with the performance of the doctors

5 50 IUI - Intrauterine Insemination

I went to the Crete Fertility Center to have an IUI (Intrauterine Insemination) appointment and I was very happy with the performance of the doctors as well as their efficiency and friendliness. I have felt that their prices were very fair.

The clinic was very good, they had good doctors, they had good prices and were very professional. I was pleased to have received such service from the clinic.

See what others think about the clinic's customer service:

Oumarou, France30.10.2022
Bobby, UK29.06.2020
Excellent - response straight away so hoping to work with the clinic soon.
Alison, UK29.04.2018
Great service but I am not in apposition to make an appointment just yet.
Muhammad, US21.09.2017
The response was good.
Rekhia, Sweden19.09.2016
Very good
Simone, Italy31.07.2015
Very good detailed information. As I have recently started my research and planning on going for egg donation it was great help.


  • ISO Certification - International Organization for Standardization (International) 
  • ESHRE - European Society of Human Reproduction and Embryology (International) 


ParkingAccessible to disabled peoplePublic transport accessWheelchair accessible toiletAccess without stepsDisabled parkingPatient bathroomWireless access

Clinic services

Emergency serviceText message remindersHome visitsOpen 24 hoursOpen weekends

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Local accommodationTranslation servicesLocal guideTours and vacation servicesPick up service from hotelPick up service from airport

Languages spoken



Egg Donation

Egg Donor


Egg Donation


Egg Freezing

Oocyte cryopreservation or vitrification (egg freezing) is a rapidly advancing, breakthrough technology in which a woman’s eggs (oocytes) are extracted, frozen and stored (oocyte bank). Later, when she is ready to become pregnant, the eggs can be thawed, fertilized, and transferred to the uterus as embryos.

Oocyte cryopreservation is aimed at three particular groups of women: those diagnosed with cancer who have not yet begun chemotherapy or radiotherapy; those undergoing treatment with assisted reproductive technologies who do not consider embryo freezing an option; and those who would like to preserve their future ability to have children, either because they do not yet have a partner, or for other personal or medical reasons.

Oocyte cryopreservation is an important option for individuals undergoing IVF who object, either for religious or ethical reasons, to the practice of freezing embryos. Having the option to fertilize only as many eggs as will be utilized in the IVF process and then freeze any remaining unfertilized eggs can be a positive solution. In this way, there are no excess embryos created, and there is no need of unused frozen embryos disposition, a practice which can create complex choices for certain individuals.

Egg freezing can also be beneficial for women who, for the purpose of education, career or other reasons, desire to postpone childbearing. Freezing eggs at an early age may ensure a chance for a future pregnancy.

Additionally, women with a family history of early menopause have an interest in fertility preservation. With egg freezing, they will have a frozen store of eggs, in the likelihood that their eggs are depleted at an early age.


Egg Sharing


Embryo Donation

Egg (or embryo) donation for IVF fertility treatments, is indicated for women who, for various reasons, do not produce eggs. In these cases, it has been proven that egg / embryo donation is a very effective procedure in a wide range of problems. The indications for egg donation or embryo donation include the following conditions:

  • Gonad dysgenesia, carrying an inheritable genetic disorder such as muscular Dystrophy or haemophilia. Such diseases can be passed on to their children. Rather than risk giving birth to a child who might suffer greatly and die at an early age, some women choose to have a chance of a perfectly healthy child via egg donation.
  • Surgical procedures to / removal or absence of ovaries (ovarian damage following surgery, radiation or chemotherapy)
  • Women born without or with under-developed ovaries (e.g. Turner’s syndrome).
  • Poor response to ovarian stimulation
  • Failure of multiple attempts of assisted reproduction methods (IVF, ICSI)
  • Early menopause. This, however, occurs much earlier to some women, even in their teens or early twenties, before they would even have contemplated starting a family. This condition is called premature ovarian failure or premature menopause.

  • Patient aged above 45 (menopause). After the menopause a woman is no longer capable of conceiving because her ovaries stop producing eggs and sex hormones.


Embryo Freezing

Embryo cryopreservation or embryo freezing is a method used to preserve embryos by cooling and storing them at low temperatures (-196°C). They can then be thawed at a future date and transferred to the uterus, providing additional opportunity for achieving conception.

As part of the usual process of in vitro fertilization, multiple eggs may be stimulated to grow, be recovered from the ovary and become fertilized. This may result in additional embryos in excess of the number that a couple would desire to have transferred back to the uterus at one time. If the additional embryos are of sufficiently good quality to undergo the process of cryopreservation, this can be performed in order to provide another opportunity for embryo transfer. Depending on the embryo stage at the time of freezing, between 60-90% survive freeze/thaw process resulting in a future pregnancy.


Fertility Specialist Consultation


FET - Frozen Embryo Transfer


ICSI - Intracytoplasmic Sperm Injection

ICSI, or Intracytoplasmic sperm injection, is a micromanipulation technique developed to help achieve fertilization for couples with severe male factor infertility or couples who have had failure to fertilize in a previous in vitro fertilization attempt (IVF).

The procedure overcomes many of the barriers to fertilization and allows couples with little hope of achieving successful pregnancy to obtain fertilized embryos. The procedure was first used at UCSF in 1994 and the first successful birth, achieved with ICSI assistance, was in February 1995. UCSF was the first San Francisco Bay Area program to achieve a pregnancy and birth with this “miracle” procedure.

How ICSI Works

The technique involves very precise manoeuvres to pick up a single live sperm and inject it directly into the centre of a human egg. The procedure requires that the female partner undergo ovarian stimulation with fertility medications so that several mature eggs develop (IVF). These eggs are then aspirated through the vagina, using vaginal ultrasound, and incubated under precise conditions in the embryology laboratory.

The semen sample is prepared by centrifuging (spinning the sperm cells through a special medium). This solution separates live sperm from debris and most of the dead sperm. The micromanipulation specialist picks up the single live sperm in a glass needle and injects it directly into the egg.

Through the ICSI procedure, many couples with difficult male factor infertility problems have achieved pregnancy. Fertilization rates of 70-80% (of all eggs injected) are currently being achieved, and pregnancy rates are comparable to those seen with IVF in couples with no male factor infertility.

Pregnancy rates in our unit are 48 – 50%, depending on the woman’s age.


IMSI - Intracytoplasmic Morphologically-Selected Sperm Injection


IUI - Intrauterine Insemination

Intra-Uterine Insemination (also known as artificial insemination) is the process of preparing and delivering sperm, so that, a highly concentrated amount of active motile sperm is placed directly through the cervix into the uterus.

IUI can be performed with or without fertility drugs for the female patient. Compared to timed intercourse, it is generally accepted that there is a 2-fold higher pregnancy rate with IUI. Thus, for infertility patients, IUI is commonly performed as a low-tech, cost-effective approach to enhancing fertility in patients. Prior to initiating IUI treatment, women must have at least one documented open fallopian tube as demonstrated by hystero – salpingogram (the tubal dye study).

There are several techniques available for preparing the sperm for IUI. All of the techniques involve separating sperm from seminal fluid. It is not possible to inject semen directly into the uterus because of chemicals in the fluid that can cause extremely painful uterine contractions.
Motile sperm are separated from dead sperm and other cells through the use of viscous solution. We will ask that the male partner bring or produce his specimen for our laboratory several hours prior to the IUI procedure.


IVF - In Vitro Fertilisation


IVF with Donor Eggs


IVM - In Vitro Maturation


Ovulation Induction

There are two different methods of ovarian stimulation (ovulation induction). The first is used for women who are not ovulating spontaneously (irregular or infrequent menstruation). In such cases, the aim is to stimulate the release of one egg a month. This is most easily done by prescribing fertility pills. If this medication is not effective, then injections of a small dose of gonadotropins may be necessary.

In the second situation, the woman is ovulating spontaneously but has unexplained infertility or her partner has mild male-factor infertility. In such a case, the aim of ovulation induction is to stimulate the production of 2 to 4 large follicles, so that several eggs will be released. This is most easily achieved by injections of gonadotropins. This treatment is combined with intra uterine insemination (IUI) to bring the sperm closer to the egg.


PGD - Preimplantation Genetic Diagnosis

Preimplantation Genetic Diagnosis (PGD) is a laboratory procedure, used in conjunction with IVF, which helps to reduce the risk of passing on inherited conditions.  Some of the most common reasons for PGD are specific single gene conditions (such as cystic fibrosis or sickle cell anemia) or structural changes of a parent’s chromosomes.  Families may also use PGD when a member of the family is in need of a bone marrow donor, as a way to have a child who can provide matching [Treatment name removed].

Typically, the couples in need of these techniques are NOT infertile. In fact, in most cases, there is a family history of the condition and the couple is seeking the opportunity to diminish the risk of having another child with significant health compromise or early death.  However, through generally available genetic screening, occasionally a couple who is seeking fertility treatment is found to be at risk of passing on an inherited condition, and PGD may become an option for them during the course of their care with us.

PGD is available for almost any inherited condition for which the exact mutation is known.  However, a unique test must usually be built for each couple who is planning to use PGD.  This test design may take up to several months to complete prior to beginning an IVFcycle.

The genetic material that is transported by generation in generation and is required for the physiologic growth of each organism is found organised in structures, the chromosomes, in the core of cells. The core of sperm is linked with the core of ovum, shaping a cell with 46 chromosomes that is to say 23 chromosomes from each core. This is the beginning of existence of your child.


PGS - Preimplantation Genetic Screening


Sperm - FISH Analysis


Sperm Freezing

Sperm from two sources can be frozen: from ejaculates or from fluid extracted in the operating room during surgical procedures (vasal, epididymal and testicular sperm specimens). The sperm cryopreservation is usually frozen for a period of one year (sperm bank); at that time, future arrangements are discussed. It is generally believed that sperm that have been through the freeze-thaw process are no more likely to result in birth defects than freshly ejaculated sperm.

Crete Fertility Centre is in co-operation with the largest sperm bank in Europe, Cryos Bank in Denmark, in order to secure the highest sperm quality standards in case of assisted reproduction with the use of donor’s sperm.

All Donors are under a state of the strictest and obligatory procedures every three months, in order to secure sperm quality. These procedures include psychological examinations, full pathological, haematological and microbiological tests in order to trace genetic abnormalities, sexually transmitted diseases and various viruses (such as hepatitis). All sperm samples become approved after being quarantined for 6 months.

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Crete Fertility Center - Dr Mattheos Fraidakis

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Dr Mattheos Fraidakis - Doctor at Crete Fertility Center

Dr Mattheos Fraidakis

Job Title:
  English, Italian, Greek
Dr. Mattheos Fraidakis MD, PhD Consultant in Obstetrics – Gynaecology
Reproductive Endocrinology and Surgery

    * PhD at Athens University
    * Clinical Fellow and Visiting Lecturer at the Joint Academic Unit of Obstetrics, Gynaecology and Reproductive Physiology at the Royal London Hospital Medical College, University of London
    * IVF UNIT, Royal London Hospital
    * Scientific Director IVF Unit Crete Fertility Centre

Dr. Mattheos Fraidakis was born in Rethymnon, Crete, Greece in 11/11/1957 and studied at the medical faculty of Rome’s University (Italy).

He undertook his specialty training at the Obstetrics-Gynaecology clinic of Athens University (Aretaeon Hospital, Athens) under Clinic Director P.A. Zourlas, where he was awarded PhD with Honours of Excellence.

He continued training in the subspecialty of ART at the Academic Unit of Obstetrics and Gynaecology at the Royal London Hospital, supervised by the Head of Unit and Director of the ART clinic, Professor J.G.Grudzinskas in the principles of assisted reproduction, endoscopic surgery and diagnosis/treatment utilising Colposcopy & Laser.

During 1991 and 1992, Dr. Fraidakis was appointed as clinical fellow and assistant researcher in the Academic Uunit of Obstetrics, – Gynecology and & Reproduction physiology, directed by under Professor J.G.Grudzinskas, at the Royal London Hospital.

During this time Dr. Fraidakis was invited to join the medical team at Bridge Fertility Centre, one of the largest centers of assisted reproductive technology in UK, at London Bridge Hospital. He also acted as visiting lecturer to the Academic Unit at the Royal London Hospital in ART and endoscopic surgery.

As Clinical and Scientific Director of the, IVF Unit Crete Fertility Centre in Heraklion, Crete, Greece, since its foundation in 1993, Dr. Fraidakis has had the privilege of successfully offering quality services in assisted reproduction to the highest clinical and scientific standards never losing focus of the specific needs of couples who have sought care at Crete Fertility Centre.

Dr. Fraidakis is a distinct member of:

    * European Society of Human Reproduction and Embryology(E.S.H.R.E.)
    * American Society for Reproduction Medicine (A.S.R.M.)
    * European Society of Gynaecological Endoscopy (E.S.G.E.)
    * Greek Society of Fertility & Infertility
    * Greek Society of Gynaecological Endoscopy
    * Greek Society of Obstetrics & Gynecology

He has published original papers in Greek and International scientific journals . Also he has presented others at International and Greek conferences.

He is regularly an invited speaker in scientific Greek and International congresses and seminars, as well as an organizer of meetings that concerns infertility ART and prevention of severe complications in IVF.

His clinical activities range from 2000 births of healthy children following successful IVF programmes, to successful reproductive surgery operations, hysteroscopic and laparoscopic operations and impregnation of people with special needs.

His research activity stems form his extensive clinical experience in combination with processing of statistical data of “Crete Fertility Centre”
with International results. The intention is to create studies , some of them have been published , while others are in press and some are at various stages of completion.
Diserythropoietic Anaimia in pregnancy
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Sofokli Venizelou & Arch. Makariou 56, Heraklion, 71202Greece

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